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The market is characterized by a wide array of treatment modalities including antihistamines, corticosteroids, immunotherapy, and emerging biologics, all aimed at managing symptoms and addressing the underlying causes of allergic reactions

Importantly, tBHP-induced cell death and HMGB1 release were largely inhibited by classic ferroptosis inhibitors such as ferrostatin-1 (Fer-1) and deferoxamine (DFO), indicating the induction of ferroptosis (Fig

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Author contributions LI: Formal analysis, Visualization, Writing original draft

PLB treatment significantly decreased iron ions and LPO, suggesting its role in ferroptosis inhibition, but YTHDF1 overexpression reversed these effects (Fig